Inactivation of Rho Signaling Pathway Promotes CNS Axon Regeneration

Regeneration in the CNS is blocked by many different growth inhibitory proteins. To foster regeneration, we have investigated a strategy to block the neuronal response to growth inhibitory signals. Here, we report that injured axons regrow directly on complex inhibitory substrates when Rho GTPase is...

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Pubblicato in:J Neurosci
Autori principali: Lehmann, Maxine, Fournier, Alyson, Selles-Navarro, Immaculada, Dergham, Pauline, Sebok, Agnes, Leclerc, Nicole, Tigyi, Gabor, McKerracher, Lisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1999
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782492/
https://ncbi.nlm.nih.gov/pubmed/10460260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-17-07537.1999
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