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Rho Kinase Inhibition Enhances Axonal Regeneration in the Injured CNS

Myelin-associated inhibitors limit axonal regeneration in the injured brain and spinal cord. A common target of many neurite outgrowth inhibitors is the Rho family of small GTPases. Activation of Rho and a downstream effector of Rho, p160ROCK, inhibits neurite outgrowth. Here, we demonstrate that Rh...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Fournier, Alyson E., Takizawa, Bayan T., Strittmatter, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742251/
https://ncbi.nlm.nih.gov/pubmed/12598630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-04-01416.2003
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