B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS

Activation of intrinsic growth programs that promote developmental axon growth may also facilitate axon regeneration in injured adult neurons. Here, we demonstrate that conditional activation of B-RAF kinase alone in mouse embryonic neurons is sufficient to drive the growth of long-range peripheral...

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Bibliografiske detaljer
Main Authors: O’Donovan, Kevin J., Ma, Kaijie, Guo, Hengchang, Wang, Chen, Sun, Fang, Han, Seung Baek, Kim, Hyukmin, Wong, Jamie K., Charron, Jean, Zou, Hongyan, Son, Young-Jin, He, Zhigang, Zhong, Jian
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010899/
https://ncbi.nlm.nih.gov/pubmed/24733831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131780
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