B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS

Activation of intrinsic growth programs that promote developmental axon growth may also facilitate axon regeneration in injured adult neurons. Here, we demonstrate that conditional activation of B-RAF kinase alone in mouse embryonic neurons is sufficient to drive the growth of long-range peripheral...

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Autors principals: O’Donovan, Kevin J., Ma, Kaijie, Guo, Hengchang, Wang, Chen, Sun, Fang, Han, Seung Baek, Kim, Hyukmin, Wong, Jamie K., Charron, Jean, Zou, Hongyan, Son, Young-Jin, He, Zhigang, Zhong, Jian
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010899/
https://ncbi.nlm.nih.gov/pubmed/24733831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131780
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