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Characterization of Progressive Motor Deficits in Mice Transgenic for the Human Huntington’s Disease Mutation
Transgenic mice expressing exon 1 of the human Huntington’s disease (HD) gene carrying a 141–157 CAG repeat (line R6/2) develop a progressive neurological phenotype with motor symptoms resembling those seen in HD. We have characterized the motor deficits in R6/2 mice using a battery of behavioral te...
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| Publicat a: | J Neurosci |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Neuroscience
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6782264/ https://ncbi.nlm.nih.gov/pubmed/10191337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-08-03248.1999 |
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