Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

Huntington's disease (HD) is a fatal inherited neurodegenerative disorder characterized by personality changes, motor impairment, and subcortical dementia. HD is one of a number of diseases caused by expression of an expanded polyglutamine repeat. We have developed several lines of mice that are tra...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Turmaine, Mark, Raza, Aysha, Mahal, Amarbirpal, Mangiarini, Laura, Bates, Gillian P., Davies, Stephen W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16675/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10869421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.110078997
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