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Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

Huntington's disease (HD) is a fatal inherited neurodegenerative disorder characterized by personality changes, motor impairment, and subcortical dementia. HD is one of a number of diseases caused by expression of an expanded polyglutamine repeat. We have developed several lines of mice that ar...

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Huvudupphovsmän: Turmaine, Mark, Raza, Aysha, Mahal, Amarbirpal, Mangiarini, Laura, Bates, Gillian P., Davies, Stephen W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC16675/
https://ncbi.nlm.nih.gov/pubmed/10869421
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