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A subpopulation of pulmonary neuroendocrine cells are reserve stem cells regulated by the tumor suppressors Rb, p53, and Notch

Pulmonary neuroendocrine (NE) cells are neurosensory cells sparsely distributed throughout the bronchial epithelium, many in innervated clusters of 20–30 cells. Following lung injury, NE cells proliferate and generate other cell types to promote epithelial repair. Here we show that only a subpopulat...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Ouadah, Youcef, Rojas, Enrique R., Riordan, Daniel P., Capostagno, Sarah, Krasnow, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782070/
https://ncbi.nlm.nih.gov/pubmed/31585080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.09.010
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