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A subpopulation of pulmonary neuroendocrine cells are reserve stem cells regulated by the tumor suppressors Rb, p53, and Notch

Pulmonary neuroendocrine (NE) cells are neurosensory cells sparsely distributed throughout the bronchial epithelium, many in innervated clusters of 20–30 cells. Following lung injury, NE cells proliferate and generate other cell types to promote epithelial repair. Here we show that only a subpopulat...

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Publicat a:Cell
Autors principals: Ouadah, Youcef, Rojas, Enrique R., Riordan, Daniel P., Capostagno, Sarah, Krasnow, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782070/
https://ncbi.nlm.nih.gov/pubmed/31585080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.09.010
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