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Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer

Rapid appearance of resistance to fibroblast growth factor receptor (FGFR) inhibitors hampers targeted regimens in bladder cancer. In the present study, we evaluated whether SIP-SII, a sulphated derivative of the polysaccharide in Sepiella maindroni (spineless cuttlefish) ink used in traditional Chi...

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Vydáno v:Aging (Albany NY)
Hlavní autoři: Shan, Liping, Liu, Wei, Zhan, Yunhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782013/
https://ncbi.nlm.nih.gov/pubmed/31545294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102286
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