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Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer

Rapid appearance of resistance to fibroblast growth factor receptor (FGFR) inhibitors hampers targeted regimens in bladder cancer. In the present study, we evaluated whether SIP-SII, a sulphated derivative of the polysaccharide in Sepiella maindroni (spineless cuttlefish) ink used in traditional Chi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Aging (Albany NY)
Päätekijät: Shan, Liping, Liu, Wei, Zhan, Yunhong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782013/
https://ncbi.nlm.nih.gov/pubmed/31545294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102286
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