miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells

Clinically, one of the principal factors in the failure of advanced colorectal cancer (CRC) treatment is chemoresistance to 5-fluorouracil (5FU)-based chemotherapy. Although microRNA-375-3p (miR-375) is considered a tumor suppressor in multiple cancers, the mechanism of miR-375 in the regulation of...

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Bibliografiska uppgifter
I publikationen:Aging (Albany NY)
Huvudupphovsmän: Xu, Xueni, Chen, Xiaoxiang, Xu, Mu, Liu, Xiangxiang, Pan, Bei, Qin, Jian, Xu, Tao, Zeng, Kaixuan, Pan, Yuqin, He, Bangshun, Sun, Huiling, Sun, Li, Wang, Shukui
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals 2019
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781994/
https://ncbi.nlm.nih.gov/pubmed/31543507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102214
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