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N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans

Axon regeneration following neuronal injury is an important repair mechanism that is not well understood at present. In Caenorhabditis elegans, axon regeneration is regulated by DDR-2, a receptor tyrosine kinase (RTK) that contains a discoidin domain and modulates the Met-like SVH-2 RTK–JNK MAP kina...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genetics
Hauptverfasser: Shimizu, Tatsuhiro, Kato, Yuka, Sakai, Yoshiki, Hisamoto, Naoki, Matsumoto, Kunihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781908/
https://ncbi.nlm.nih.gov/pubmed/31371405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302492
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