Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor

In Caenorhabditis elegans, axon regeneration is activated by a signaling cascade through the receptor tyrosine kinase (RTK) SVH-2. Axonal injury induces svh-2 gene expression by degradation of the Mad-like transcription factor MDL-1. In this study, we identify the svh-24/sdz-33 gene encoding a prote...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shimizu, Tatsuhiro, Pastuhov, Strahil I., Hanafusa, Hiroshi, Sakai, Yoshiki, Todoroki, Yasuko, Hisamoto, Naoki, Matsumoto, Kunihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984584/
https://ncbi.nlm.nih.gov/pubmed/33514673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1024-20.2021
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