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Antiviral therapy may decrease HBx, affecting cccDNA and MSL2 in hepatocarcinogenesis
Chronic hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC). Covalently closed circular DNA (cccDNA) is an intermediate in the life cycle of HBV. HBV-encoded X protein (HBx), a key viral oncoprotein, can be specifically ubiquitylated by male specific lethal 2 (MSL2), which...
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| Gepubliceerd in: | Oncol Lett |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
D.A. Spandidos
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6781749/ https://ncbi.nlm.nih.gov/pubmed/31612010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10833 |
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