Antiviral therapy may decrease HBx, affecting cccDNA and MSL2 in hepatocarcinogenesis

Chronic hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC). Covalently closed circular DNA (cccDNA) is an intermediate in the life cycle of HBV. HBV-encoded X protein (HBx), a key viral oncoprotein, can be specifically ubiquitylated by male specific lethal 2 (MSL2), which...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncol Lett
Auteurs principaux: Jin, Xue-Li, Hong, Suk Kyun, Kim, Hwajung, Lee, Sun-Kyung, Yi, Nam-Joon, Lee, Kwang-Woong, Suh, Kyung-Suk
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2019
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781749/
https://ncbi.nlm.nih.gov/pubmed/31612010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10833
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires