Genome-wide allele-specific methylation is enriched at gene regulatory regions in a multi-generation pedigree from the Norfolk Island isolate

BACKGROUND: Allele-specific methylation (ASM) occurs when DNA methylation patterns exhibit asymmetry among alleles. ASM occurs at imprinted loci, but its presence elsewhere across the human genome is indicative of wider importance in terms of gene regulation and disease risk. Here, we studied ASM by...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Epigenetics Chromatin
Egile Nagusiak: Benton, Miles C., Lea, Rodney A., Macartney-Coxson, Donia, Sutherland, Heidi G., White, Nicole, Kennedy, Daniel, Mengersen, Kerry, Haupt, Larisa M., Griffiths, Lyn R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781349/
https://ncbi.nlm.nih.gov/pubmed/31594537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0304-7
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