Methylome-wide association study of whole blood DNA in the Norfolk Island isolate identifies robust loci associated with age

Epigenetic regulation of various genomic functions, including gene expression, provide mechanisms whereby an organism can dynamically respond to changes in its environment and modify gene expression accordingly. One epigenetic mechanism implicated in human aging and age-related disorders is DNA meth...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Aging (Albany NY)
Main Authors: Benton, Miles C., Sutherland, Heidi G., Macartney-Coxson, Donia, Haupt, Larisa M., Lea, Rodney A., Griffiths, Lyn R.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391229/
https://ncbi.nlm.nih.gov/pubmed/28255110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101187
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