Circulating extracellular vesicle content reveals de novo DNA methyltransferase expression as a molecular method to predict septic shock

Extracellular vesicles (EVs) are mRNA-containing cell fragments shed into circulation during pathophysiological events. DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) regulate gene expression by modifying DNA methylation and altering transcription. Sepsis is a systemic insult resulting in vascul...

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Pubblicato in:J Extracell Vesicles
Autori principali: Dakhlallah, Duaa A., Wisler, Jon, Gencheva, Marieta, Brown, Candice M., Leatherman, Erin R., Singh, Kanhaiya, Brundage, Kathy, Karsies, Todd, Dakhlallah, Ahmad, Witwer, Kenneth W., Sen, Chandan K., Eubank, Timothy D., Marsh, Clay B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781191/
https://ncbi.nlm.nih.gov/pubmed/31632618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2019.1669881
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