Circulating extracellular vesicle content reveals de novo DNA methyltransferase expression as a molecular method to predict septic shock

Extracellular vesicles (EVs) are mRNA-containing cell fragments shed into circulation during pathophysiological events. DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) regulate gene expression by modifying DNA methylation and altering transcription. Sepsis is a systemic insult resulting in vascul...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Dakhlallah, Duaa A., Wisler, Jon, Gencheva, Marieta, Brown, Candice M., Leatherman, Erin R., Singh, Kanhaiya, Brundage, Kathy, Karsies, Todd, Dakhlallah, Ahmad, Witwer, Kenneth W., Sen, Chandan K., Eubank, Timothy D., Marsh, Clay B.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781191/
https://ncbi.nlm.nih.gov/pubmed/31632618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2019.1669881
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