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Towards the Oral Treatment of Ileo-Colonic Inflammatory Bowel Disease with Infliximab Tablets: Development and Validation of the Production Process

Infliximab (IFX) is an intravenously administered monoclonal antibody antagonizing the effects of tumor necrosis factor-alpha (TNF) systemically and is efficacious in the treatment of inflammatory bowel disease (IBD). However, studies suggest that the anti-inflammatory effects result from local immu...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Gareb, Bahez, Posthumus, Silke, Beugeling, Max, Koopmans, Pauline, Touw, Daan J., Dijkstra, Gerard, Kosterink, Jos G.W., Frijlink, Henderik W.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781063/
https://ncbi.nlm.nih.gov/pubmed/31450748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11090428
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