Prediction of the Ease of Subdivision of Scored Tablets from Their Physical Parameters

At present, the ease of subdivision of scored tablets is estimated in vivo. In order to replace such in vivo testing and to develop a surrogate test which uses in vitro techniques, the association between physical parameters of scored tablets and their ease of subdivision was studied. The physical p...

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Главные авторы: van der Steen, Koos C., Frijlink, Henderik W., Schipper, C. Maarten A., Barends, Dirk M.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2010
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850449/
https://ncbi.nlm.nih.gov/pubmed/20077042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9365-4
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