A low dose of AZD8055 enhances radiosensitivity of nasopharyngeal carcinoma cells by activating autophagy and apoptosis

Activation of the PI3K/mTOR pathways is significantly correlated with a poor prognosis in nasopharyngeal carcinoma (NPC). Inhibition of these pathways was reported to be effective in restoring radiosensitivity. In this study, the activity of the novel ATP-competitive, orally bioavailable mTOR inhibi...

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Pubblicato in:Am J Cancer Res
Autori principali: Chang, Lihong, Huang, Zizhen, Li, Shuaixiang, Yao, Zhouzhou, Bao, Hongwei, Wang, Zhiyuan, Li, Xia, Chen, Xiaohong, Huang, Jiancong, Zhang, Gehua
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780664/
https://ncbi.nlm.nih.gov/pubmed/31598395
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