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Is Alzheimer disease a failure of mobilizing immune defense? Lessons from cognitively fit oldest-old

Multifaceted evidence supports the hypothesis that inflammatory-immune mechanisms contribute to Alzheimer disease (AD) neuropathology and genetic association of several immune specific genes (TREM2, CR1, and CD33) suggests that maladaptive immune responses may be pivotal drivers of AD pathogenesis....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Dialogues Clin Neurosci
Egile Nagusiak: Katsel, Pavel, Haroutunian, Vahram
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Les Laboratoires Servier 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780355/
https://ncbi.nlm.nih.gov/pubmed/31607776
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