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Is Alzheimer disease a failure of mobilizing immune defense? Lessons from cognitively fit oldest-old
Multifaceted evidence supports the hypothesis that inflammatory-immune mechanisms contribute to Alzheimer disease (AD) neuropathology and genetic association of several immune specific genes (TREM2, CR1, and CD33) suggests that maladaptive immune responses may be pivotal drivers of AD pathogenesis....
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| Publicado no: | Dialogues Clin Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Les Laboratoires Servier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6780355/ https://ncbi.nlm.nih.gov/pubmed/31607776 |
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