Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection

BACKGROUND AND PURPOSE: Severe influenza A virus (IAV) infections are associated with damaging hyperinflammation that can be fatal. There is an urgent need to identify new therapeutic agents to treat severe and pathogenic IAV infections. Repurposing of drugs with an existing and studied pharmacokine...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Rosli, Sarah, Kirby, Francis J., Lawlor, Kate E., Rainczuk, Kate, Drummond, Grant R., Mansell, Ashley, Tate, Michelle D.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780046/
https://ncbi.nlm.nih.gov/pubmed/31271646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14787
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