FACT mediates cohesin function on chromatin

Cohesin is a regulator of genome architecture with roles in sister chromatid cohesion and chromosome compaction. The recruitment and mobility of cohesin complexes on DNA is restricted by nucleosomes. Here we show that the role of cohesin in chromosome organisation requires the histone chaperone FACT...

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Publicat a:Nat Struct Mol Biol
Autors principals: Garcia-Luis, Jonay, Lazar-Stefanita, Luciana, Gutierrez-Escribano, Pilar, Thierry, Agnes, Cournac, Axel, García, Alicia, González, Sara, Sánchez, Mar, Jarmuz, Adam, Montoya, Alex, Dore, Marian, Kramer, Holger, Karimi, Mohammad Mehdi, Antequera, Francisco, Koszul, Romain, Aragon, Luis
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779571/
https://ncbi.nlm.nih.gov/pubmed/31582854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0307-x
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