FACT mediates cohesin function on chromatin

Cohesin is a regulator of genome architecture with roles in sister chromatid cohesion and chromosome compaction. The recruitment and mobility of cohesin complexes on DNA is restricted by nucleosomes. Here we show that the role of cohesin in chromosome organisation requires the histone chaperone FACT...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Garcia-Luis, Jonay, Lazar-Stefanita, Luciana, Gutierrez-Escribano, Pilar, Thierry, Agnes, Cournac, Axel, García, Alicia, González, Sara, Sánchez, Mar, Jarmuz, Adam, Montoya, Alex, Dore, Marian, Kramer, Holger, Karimi, Mohammad Mehdi, Antequera, Francisco, Koszul, Romain, Aragon, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779571/
https://ncbi.nlm.nih.gov/pubmed/31582854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0307-x
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