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The effect of dose and selection of two different ligands on the deposition and antitumor efficacy of targeted nanoparticles in brain tumors

Deposition of nanoparticles to tumors often can be enhanced by targeting receptors overexpressed in a tumor. However, a tumor may exhibit a finite number of a biomarker that is accessible and targetable by nanoparticles, limiting the available landing spots. To explore this, we selected two differen...

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Publicado en:Mol Pharm
Autores principales: Turan, Oguz, Bielecki, Peter, Tong, Kathleen, Covarrubias, Gil, Moon, Taylor, Rahmy, Abdelrahman, Cooley, Shane, Park, Youngjun, Peiris, Pubudu M., Ghaghada, Ketan B., Karathanasis, Efstathios
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779508/
https://ncbi.nlm.nih.gov/pubmed/31442061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00693
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