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The effect of dose and selection of two different ligands on the deposition and antitumor efficacy of targeted nanoparticles in brain tumors

Deposition of nanoparticles to tumors often can be enhanced by targeting receptors overexpressed in a tumor. However, a tumor may exhibit a finite number of a biomarker that is accessible and targetable by nanoparticles, limiting the available landing spots. To explore this, we selected two differen...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Pharm
Autori principali: Turan, Oguz, Bielecki, Peter, Tong, Kathleen, Covarrubias, Gil, Moon, Taylor, Rahmy, Abdelrahman, Cooley, Shane, Park, Youngjun, Peiris, Pubudu M., Ghaghada, Ketan B., Karathanasis, Efstathios
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779508/
https://ncbi.nlm.nih.gov/pubmed/31442061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00693
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