The effect of dose and selection of two different ligands on the deposition and antitumor efficacy of targeted nanoparticles in brain tumors

Deposition of nanoparticles to tumors often can be enhanced by targeting receptors overexpressed in a tumor. However, a tumor may exhibit a finite number of a biomarker that is accessible and targetable by nanoparticles, limiting the available landing spots. To explore this, we selected two differen...

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Bibliografiske detaljer
Udgivet i:Mol Pharm
Main Authors: Turan, Oguz, Bielecki, Peter, Tong, Kathleen, Covarrubias, Gil, Moon, Taylor, Rahmy, Abdelrahman, Cooley, Shane, Park, Youngjun, Peiris, Pubudu M., Ghaghada, Ketan B., Karathanasis, Efstathios
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779508/
https://ncbi.nlm.nih.gov/pubmed/31442061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00693
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