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Stimulation of Piezo1 by mechanical signals promotes bone anabolism
Mechanical loading, such as caused by exercise, stimulates bone formation by osteoblasts and increases bone strength, but the mechanisms are poorly understood. Osteocytes reside in bone matrix, sense changes in mechanical load, and produce signals that alter bone formation by osteoblasts. We report...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779475/ https://ncbi.nlm.nih.gov/pubmed/31588901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49631 |
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