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Stimulation of Piezo1 by mechanical signals promotes bone anabolism

Mechanical loading, such as caused by exercise, stimulates bone formation by osteoblasts and increases bone strength, but the mechanisms are poorly understood. Osteocytes reside in bone matrix, sense changes in mechanical load, and produce signals that alter bone formation by osteoblasts. We report...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Li, Xuehua, Han, Li, Nookaew, Intawat, Mannen, Erin, Silva, Matthew J, Almeida, Maria, Xiong, Jinhu
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779475/
https://ncbi.nlm.nih.gov/pubmed/31588901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49631
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