IL-1β/TNF-α/IL-6 inflammatory cytokines promote STAT1-dependent induction of CH25H in Zika virus–infected human macrophages

Zika virus (ZIKV)(3) is an enveloped, single-stranded, positive-sense RNA virus of the Flaviviridae family that has emerged as a public health threat because of its global transmission and link to microcephaly. Currently there is no vaccine for this virus. Conversion of cholesterol to 25-hydroxychol...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Magoro, Tshifhiwa, Dandekar, Aditya, Jennelle, Lucas T., Bajaj, Rohan, Lipkowitz, Gabriel, Angelucci, Angelina R., Bessong, Pascal O., Hahn, Young S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779448/
https://ncbi.nlm.nih.gov/pubmed/31375561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007555
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