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Targeted sequencing reveals expanded genetic diversity of human transfer RNAs

Transfer RNAs are required to translate genetic information into proteins as well as regulate other cellular processes. Nucleotide changes in tRNAs can result in loss or gain of function that impact the composition and fidelity of the proteome. Despite links between tRNA variation and disease, the i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:RNA Biol
Päätekijät: Berg, Matthew D., Giguere, Daniel J., Dron, Jacqueline S., Lant, Jeremy T., Genereaux, Julie, Liao, Calwing, Wang, Jian, Robinson, John F., Gloor, Gregory B., Hegele, Robert A., O’Donoghue, Patrick, Brandl, Christopher J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779403/
https://ncbi.nlm.nih.gov/pubmed/31407949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1646079
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