APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis

BACKGROUND: Two coding variants in the apo L1 gene (APOL1) are strongly associated with kidney disease in blacks. Kidney disease itself increases the risk of cardiovascular disease, but whether these variants have an independent direct effect on the risk of cardiovascular disease is unclear. Previou...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Grams, Morgan E., Surapaneni, Aditya, Ballew, Shoshana H., Appel, Lawrence J., Boerwinkle, Eric, Boulware, L. Ebony, Chen, Teresa K., Coresh, Josef, Cushman, Mary, Divers, Jasmin, Gutiérrez, Orlando M., Irvin, Marguerite R., Ix, Joachim H., Kopp, Jeffrey B., Kuller, Lewis H., Langefeld, Carl D., Lipkowitz, Michael S., Mukamal, Kenneth J., Musani, Solomon K., Naik, Rakhi P., Pajewski, Nicholas M., Peralta, Carmen A., Tin, Adrienne, Wassel, Christina L., Wilson, James G., Winkler, Cheryl A., Young, Bessie A., Zakai, Neil A., Freedman, Barry I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Meta-Analysis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779370/
https://ncbi.nlm.nih.gov/pubmed/31383730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019030240
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