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APOL1 Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults

OBJECTIVE: We sought to evaluate the cardiovascular impact of coding variants in the apolipoprotein L1 gene APOL1 that protect against trypanosome infection but have been associated with kidney disease among African-Americans. APPROACH AND RESULTS: As part of the Cardiovascular Health Study, a popul...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Mukamal, Kenneth J., Tremaglio, Joseph, Friedman, David J., Ix, Joachim H., Kuller, Lewis H., Tracy, Russell P., Pollak, Martin R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732891/
https://ncbi.nlm.nih.gov/pubmed/26634651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305970
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