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Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B Cells

The B cell survival cytokine BAFF has been linked with the pathogenesis of systemic lupus erythematosus (SLE). BAFF binds distinct BAFF-family surface receptors, including the BAFF-R and transmembrane activator and CAML interactor (TACI). Although originally characterized as a negative regulator of...

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Bibliographic Details
Published in:J Immunol
Main Authors: Du, Samuel W., Jacobs, Holly M., Arkatkar, Tanvi, Rawlings, David J., Jackson, Shaun W.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779322/
https://ncbi.nlm.nih.gov/pubmed/30373855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800393
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