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Generation of functional murine CD11c(+) age-associated B cells in the absence of B cell T-bet expression

Age-associated B cells (ABC), a novel subset of activated B cells defined by CD11b and CD11c expression, have been linked with both protective anti-viral responses and the pathogenesis of systemic autoimmunity. Expression of the T(H)1 lineage transcription factor T-bet has been identified as a defin...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Immunol
Hauptverfasser: Du, Samuel W., Arkatkar, Tanvi, Jacobs, Holly M., Rawlings, David J., Jackson, Shaun W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779321/
https://ncbi.nlm.nih.gov/pubmed/30353919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201847641
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