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A rapid, low pH, nutrient stress, assay to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis

There is an urgent need for new anti-tubercular agents which can lead to a shortened treatment time by targeting persistent or non-replicating bacilli. In order to assess compound activity against non-replicating Mycobacterium tuberculosis, we developed a method to detect the bactericidal activity o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Early, Julie V., Mullen, Steven, Parish, Tanya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779252/
https://ncbi.nlm.nih.gov/pubmed/31589621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222970
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