Radiosynthesis and Preclinical Evaluation of (11)C-VA426, a Cyclooxygenase-2 Selective Ligand

Cyclooxygenase-2 (COX-2) is involved in the inflammatory response, and its recurrent overexpression in cancers as well as in neurodegenerative disorders has made it an important target for therapy. For this reason, noninvasive imaging of COX-2 expression may represent an important diagnostic tool. I...

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Detalhes bibliográficos
Publicado no:Contrast Media Mol Imaging
Main Authors: Carpinelli, Assunta, Rainone, Paolo, Belloli, Sara, Reale, Annalisa, Cappelli, Andrea, Germano, Giuliani, Murtaj, Valentina, Coliva, Angela, Di Grigoli, Giuseppe, Valeri, Angela, Gilardi, Maria Carla, Gianolli, Luigi, Anzini, Maurizio, Moresco, Rosa Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778861/
https://ncbi.nlm.nih.gov/pubmed/31598112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5823261
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