Radiosynthesis and Preclinical Evaluation of (11)C-VA426, a Cyclooxygenase-2 Selective Ligand

Cyclooxygenase-2 (COX-2) is involved in the inflammatory response, and its recurrent overexpression in cancers as well as in neurodegenerative disorders has made it an important target for therapy. For this reason, noninvasive imaging of COX-2 expression may represent an important diagnostic tool. I...

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Dades bibliogràfiques
Publicat a:Contrast Media Mol Imaging
Autors principals: Carpinelli, Assunta, Rainone, Paolo, Belloli, Sara, Reale, Annalisa, Cappelli, Andrea, Germano, Giuliani, Murtaj, Valentina, Coliva, Angela, Di Grigoli, Giuseppe, Valeri, Angela, Gilardi, Maria Carla, Gianolli, Luigi, Anzini, Maurizio, Moresco, Rosa Maria
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778861/
https://ncbi.nlm.nih.gov/pubmed/31598112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5823261
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