Radiosynthesis and Preclinical Evaluation of (11)C-VA426, a Cyclooxygenase-2 Selective Ligand

Cyclooxygenase-2 (COX-2) is involved in the inflammatory response, and its recurrent overexpression in cancers as well as in neurodegenerative disorders has made it an important target for therapy. For this reason, noninvasive imaging of COX-2 expression may represent an important diagnostic tool. I...

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Vydáno v:Contrast Media Mol Imaging
Hlavní autoři: Carpinelli, Assunta, Rainone, Paolo, Belloli, Sara, Reale, Annalisa, Cappelli, Andrea, Germano, Giuliani, Murtaj, Valentina, Coliva, Angela, Di Grigoli, Giuseppe, Valeri, Angela, Gilardi, Maria Carla, Gianolli, Luigi, Anzini, Maurizio, Moresco, Rosa Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778861/
https://ncbi.nlm.nih.gov/pubmed/31598112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5823261
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