Radiosynthesis and Preclinical Evaluation of (11)C-VA426, a Cyclooxygenase-2 Selective Ligand

Cyclooxygenase-2 (COX-2) is involved in the inflammatory response, and its recurrent overexpression in cancers as well as in neurodegenerative disorders has made it an important target for therapy. For this reason, noninvasive imaging of COX-2 expression may represent an important diagnostic tool. I...

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Bibliografiske detaljer
Udgivet i:Contrast Media Mol Imaging
Main Authors: Carpinelli, Assunta, Rainone, Paolo, Belloli, Sara, Reale, Annalisa, Cappelli, Andrea, Germano, Giuliani, Murtaj, Valentina, Coliva, Angela, Di Grigoli, Giuseppe, Valeri, Angela, Gilardi, Maria Carla, Gianolli, Luigi, Anzini, Maurizio, Moresco, Rosa Maria
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778861/
https://ncbi.nlm.nih.gov/pubmed/31598112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5823261
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