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Drug Delivery Nanoparticles with Locally Tunable Toxicity Made Entirely from a Light-Activatable Prodrug of Doxorubicin

PURPOSE: A major challenge facing nanoparticle-based delivery of chemotherapy agents is the natural and unavoidable accumulation of these particles in healthy tissue resulting in local toxicity and dose-limiting side effects. To address this issue, we have designed and characterized a new prodrug na...

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Vydáno v:Pharm Res
Hlavní autoři: Schutt, Carolyn, Ibsen, Stuart, Zahavy, Eran, Aryal, Santosh, Kuo, Stacey, Esener, Selin, Berns, Michael, Esener, Sadik
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778288/
https://ncbi.nlm.nih.gov/pubmed/28791550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2205-4
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