A Novel Doxorubicin Prodrug with Controllable Photolysis Activation for Cancer Chemotherapy

PURPOSE: Doxorubicin (DOX) is a very effective anticancer agent. However, in its pure form, its application is limited by significant cardiotoxic side effects. The purpose of this study was to develop a controllably activatable chemotherapy prodrug of DOX created by blocking its free amine group wit...

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Bibliographic Details
Main Authors: Ibsen, Stuart, Zahavy, Eran, Wrasdilo, Wolf, Berns, Michael, Chan, Michael, Esener, Sadik
Format: Artigo
Language:Inglês
Published: Springer US 2010
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916115/
https://ncbi.nlm.nih.gov/pubmed/20596761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0183-x
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