Differential requirements for FcγR engagement by protective antibodies against Ebola virus

Ebola virus (EBOV) continues to pose significant threats to global public health, requiring ongoing development of multiple strategies for disease control. To date, numerous monoclonal antibodies (mAbs) that target the EBOV glycoprotein (GP) have demonstrated potent protective activity in animal dis...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Bournazos, Stylianos, DiLillo, David J., Goff, Arthur J., Glass, Pamela J., Ravetch, Jeffrey V.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778250/
https://ncbi.nlm.nih.gov/pubmed/31484758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911842116
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