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Mouse model recapitulating human Fcγ receptor structural and functional diversity
The in vivo biological activities of IgG antibodies result from their bifunctional nature, in which antigen recognition by the Fab is coupled to the effector and immunomodulatory diversity found in the Fc domain. This diversity, resulting from both amino acid and glycan heterogeneity, is translated...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341029/ https://ncbi.nlm.nih.gov/pubmed/22474370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203954109 |
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