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Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes
A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected individuals. This occludes blood flow, leads to inflammation, and increases parasitemia by reducing spleen-mediated clearance of...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778195/ https://ncbi.nlm.nih.gov/pubmed/31527263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911900116 |
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