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In silico guided reconstruction and analysis of ICAM-1-binding var genes from Plasmodium falciparum
The Plasmodium falciparum variant surface antigen PfEMP1 expressed on the surface of infected erythrocytes is thought to play a major role in the pathology of severe malaria. As the sequence pool of the var genes encoding PfEMP1 expands there are opportunities, despite the high degree of sequence di...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818487/ https://ncbi.nlm.nih.gov/pubmed/29459671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21591-8 |
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