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In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36

BACKGROUND: Sequestration of parasitized red blood cells from the peripheral circulation during an infection with Plasmodium falciparum is caused by an interaction between the parasite protein PfEMP1 and receptors on the surface of host endothelial cells, known as cytoadherence. Several lines of evi...

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Dettagli Bibliografici
Pubblicato in:Malar J
Autori principali: Mustaffa, Khairul M. F., Storm, Janet, Whittaker, Megan, Szestak, Tadge, Craig, Alister G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499065/
https://ncbi.nlm.nih.gov/pubmed/28679447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1930-9
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