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In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36

BACKGROUND: Sequestration of parasitized red blood cells from the peripheral circulation during an infection with Plasmodium falciparum is caused by an interaction between the parasite protein PfEMP1 and receptors on the surface of host endothelial cells, known as cytoadherence. Several lines of evi...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Mustaffa, Khairul M. F., Storm, Janet, Whittaker, Megan, Szestak, Tadge, Craig, Alister G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499065/
https://ncbi.nlm.nih.gov/pubmed/28679447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1930-9
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