Mapping the Binding Site of a Cross-Reactive Plasmodium falciparum PfEMP1 Monoclonal Antibody Inhibitory of ICAM-1 Binding

The virulence of Plasmodium falciparum is linked to the ability of infected erythrocytes (IE) to adhere to the vascular endothelium, mediated by P. falciparum erythrocyte membrane protein 1 (PfEMP1). In this article, we report the functional characterization of an mAb that recognizes a panel of PfEM...

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Veröffentlicht in:J Immunol
Hauptverfasser: Lennartz, Frank, Bengtsson, Anja, Olsen, Rebecca W., Joergensen, Louise, Brown, Alan, Remy, Louise, Man, Petr, Forest, Eric, Barfod, Lea K., Adams, Yvonne, Higgins, Matthew K., Jensen, Anja T. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: AAI 2015
Schlagworte:
Infectious Disease and Host Response
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574524/
https://ncbi.nlm.nih.gov/pubmed/26320251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501404
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